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Emergency Action Plan

Know exactly what to do when a severe allergic reaction occurs. This step-by-step guide will help you respond quickly and effectively in an emergency.

In a real emergency, call for help immediately

911 (US) | 999 (UK) | 112 (EU) | Your local emergency number

Emergency Response

What to Do: Step-by-Step

Follow these steps in order when responding to a severe allergic reaction (anaphylaxis).

1

Recognize the Reaction

Identify signs of a severe allergic reaction: difficulty breathing, swelling of throat/tongue, rapid pulse, dizziness, widespread hives.

2

Call Emergency Services

Call 911 (US), 999 (UK), 112 (EU), or your local emergency number immediately. State that someone is having a severe allergic reaction.

3

Use Epinephrine

If an epinephrine auto-injector is available and prescribed, use it immediately. Inject into the outer thigh, through clothing if needed.

4

Position the Person

Help them lie down with legs elevated (unless breathing is difficult—then have them sit up). If vomiting, turn on their side.

5

Monitor & Wait for Help

Stay with them, monitor breathing and consciousness. Be prepared to give a second dose of epinephrine after 5-15 minutes if needed.

Quick Reference

Do's and Don'ts

Important guidelines to remember during an allergic emergency.

DO
  • Stay calm and act quickly
  • Call emergency services immediately
  • Use epinephrine if prescribed and available
  • Help them lie down with legs elevated
  • Loosen tight clothing
  • Cover them with a blanket to prevent shock
  • Stay with them until help arrives
  • Note the time epinephrine was given
  • Be prepared for CPR if they stop breathing
DON'T
  • Don't wait to see if symptoms improve
  • Don't hesitate to use epinephrine
  • Don't have them sit up if they feel faint
  • Don't give them anything to drink
  • Don't leave them alone
  • Don't assume they're fine after epinephrine
  • Don't use an expired auto-injector if a current one is available
After Treatment

What to Do After Using Epinephrine

Epinephrine is not the end of treatment—it's the first step. Here's what comes next.

  • 1Always call 911 even if symptoms improve
  • 2Note the exact time the injection was given
  • 3Keep the person lying down with legs elevated
  • 4Monitor for return of symptoms (biphasic reaction)
  • 5A second dose may be needed after 5-15 minutes
  • 6Go to the emergency room for observation (at least 4 hours)
  • 7Follow up with an allergist afterward

Biphasic Reactions

Up to 20% of anaphylaxis cases can have a second wave of symptoms (biphasic reaction) hours after the initial reaction, even after treatment. This is why emergency room observation is critical.
Second Dose Information

A second dose of epinephrine may be needed if symptoms don't improve or return within 5-15 minutes after the first injection.

Always follow the specific instructions provided with your auto-injector and consult your healthcare provider about when a second dose is appropriate.

Learn How to Use an EpiPen
Downloads

Printable Resources

Download and print these resources to keep on hand for emergencies.

Emergency Action Plan
One-page printable checklist for responding to anaphylaxis. Keep copies at home, school, and work.
Allergy Action Card
Wallet-sized card with your allergy information and emergency contacts. Customize and print.
EpiPen Quick Guide
Visual step-by-step instructions for using an epinephrine auto-injector. Great for training.

Educational Disclaimer

This information is for educational purposes only and should not replace professional medical advice or an individualized emergency action plan from your healthcare provider. In a real emergency, always call your local emergency services and follow the specific instructions provided by your healthcare provider and on your prescribed medications.